Computational genomics
Our research lies at the intersection of computer science, statistics, and genetics.
Genomics software development
The development of innovative algorithms and effective, easy to use tools for genomics research is a primary focus in our lab.
Prioritizing genetic variation.
We have developed GEMINI, a powerful framework for interpreting genetic variation in studies of human disease.
Genome arithmetic.
We maintain BEDTOOLS, the swiss army knife for genome arithmetic and the exploration of genome features/intervals.
Cancer genomics
We use genomics to study cancer biology and to understand the cellular and mutational origins of cancer.
The genetic basis of disease
We are involved in several exciting collaborations studying the genetic basis of Type 1 diabetes, extreme sensitivity to ionizing radiation and the genomics of glioblastoma.